| File No |
Title |
Author |
Journal |
Vol&Page |
Year |
Pub Med ID |
Study |
疾患 |
症例数 |
Review |
| 001001 |
癌集学的治療における ex vivo cell therapyの意義 |
山口佳之, 大田耕司, 峠哲哉 |
癌治療と宿主 |
12（2）：172-8 |
2000 |
|
単群 |
肺 |
1 |
○ |
| 001002 |
Clinical efficacy of LAK cell adoptive immunotherapy in advanced cancer patients |
Toge T, Takayama T, Kegoya Y, Kuninobu H, Yamaguchi Y, Hattori T. |
Nippon Geka Gakkai Zasshi. |
90(9):1455-8. |
1989 |
2586438 |
単群 |
食道、肺、胃、肝、乳、膵、大腸、腎、骨・軟部、その他 |
32（5+2+7+10+1
+2+1+1+2+1） |
|
| 001003 |
LAK cell adoptive immunotherapy and its problems |
Yamaguchi Y, Takayama T, Kawami H, Sato Y, Baba N, Kuroi K, Toge T. |
Nippon Geka Gakkai Zasshi. |
92(9):1234-6. |
1991 |
1944194 |
単群 |
肝、胃、腎、乳、胆、骨・軟部、大腸 |
10（2+1+3+1+1+1+1） |
|
| 001005 |
Analytical study of the clinical response to two distinct adoptive immunotherapies for advanced hepatocellular carcinoma: comparison between LAK cell and CTL therapy. |
Haruta I, Yamauchi K, Aruga A, Komatsu T, Takasaki K, Hayashi N, Hanyu F. |
J Immunother Emphasis Tumor Immunol. |
19(3):218-23. |
1996 |
8811496 |
比較 |
肝 |
18 |
|
| 001006 |
Transcatheter arterial injection of autologous lymphokine-activated killer (LAK) cells into patients with liver cancers. |
Komatsu T, Yamauchi K, Furukawa T, Obata H. |
J Clin Immunol. |
10(3):167-74. |
1990 |
2164039 |
単群 |
肺 |
26 |
|
| 001007 |
CTL療法 |
有賀淳、高崎 健 |
血液・腫瘍科 |
38(1): 45-52 |
1999 |
|
単群 |
肝 |
20 |
|
| 001009 |
固層化CD3抗体により活性化したT Cell(CD3-LAK)を用いた養子免疫療法 |
関根 暉彬 |
Biotherapy |
4(10)1606-1613 |
1990 |
|
比較 |
不明 |
25 |
|
| 001010 |
Complete remission of recurrent glioblastoma multiforme following local infusions of lymphokine activated killer cells. Case report. |
Naganuma H, Kimurat R, Sasaki A, Fukamachi A, Nukui H, Tasaka K. |
Acta Neurochir (Wien). |
99(3-4):157-60. |
1989 |
2549767 |
単群 |
脳 |
1 |
|
| 001011 |
Combined immunotherapy using interferon-alpha, interleukin-2 and lymphokine-activated killer cells--improvement of quality of life in patients with advanced renal cell carcinoma |
Watanabe J, Hattori T, Satoh M, Akimoto M. |
Nippon Hinyokika Gakkai Zasshi. |
86(6):1156-63. |
1995 |
7609359 |
単群 |
腎 |
8 |
|
| 001012 |
Use of human leukocyte antigen-mismatched allogeneic lymphokine-activated killer cells and interleukin-2 in the adoptive immunotherapy of patients with malignancies. |
Kimoto Y. |
Hum Cell. |
5(3):226-35. |
1995 |
1467321 |
単群 |
乳、頭頸部、骨・軟部、大腸、女性生殖器、皮膚、腎、胆、その他 |
14（1+1+2+4
+1+1+1+1+2） |
|
| 001013 |
Recurrence with tumor bleeding in a patient with malignant astrocytoma during the treatment with intracranial injection of lymphokine-activated killer cells--a case report |
Nagane M, Oyama H, Shibui S, Nomura K. |
No To Shinkei. |
45(6):547-51. |
1993 |
8395864 |
単群 |
脳 |
1 |
|
| 001014 |
Study of adoptive immunotherapy for metastatic renal cell carcinoma with lymphokine-activated killer (LAK) cells and interleukin-2. II. Clinical evaluation |
Nomura K, Fujioka T. |
Nippon Hinyokika Gakkai Zasshi. |
84(5):831-40. |
1993 |
8320888 |
単群 |
腎 |
11 |
|
| 001015 |
Effect of local administration of lymphokine-activated killer cells and interleukin-2 on malignant brain tumor patients. |
Ibayashi Y, Yamaki T, Kawahara T, Daibo M, Kubota T, Uede T, Tanabe S, Hashi K. |
Neurol Med Chir (Tokyo). |
Jul;33(7):448-57. |
1993 |
7692323 |
単群 |
脳 |
9 |
|
| 001016 |
Adoptive immunotherapy in patients with multiple hepatic cancers using lymphokine activated killer cells (LAK) and interleukin-2 |
Kanai T, Monden M, Takeda T, Gotoh M, Sakon M, Umeshita K, Hasuike Y, Sakita I, Nakano H, Yoshida T, et al. |
Gan To Kagaku Ryoho. |
20(11):1457-60. |
1993 |
8396896 |
単群 |
肝 |
4 |
|
| 001017 |
Usefulness and limitation of immunotherapy of metastatic renal cell carcinoma with autologous lymphokine-activated killer cells and interleukin 2 |
Nakano E, Iwasaki A, Seguchi T, Sugao H, Tada Y, Matsuda M, Sonoda T. |
Nippon Hinyokika Gakkai Zasshi. |
82(3):395-404. |
1991 |
2072602 |
単群 |
腎 |
14 |
|
| 001018 |
Study on adoptive immunotherapy in patients with renal cell carcinoma. II. Plasmapheresis with adoptive immunotherapy using LAK cells and IL-2 |
Usui A. |
Nippon Hinyokika Gakkai Zasshi. |
81(7):1058-64. |
1990 |
2214469 |
単群 |
腎 |
10 |
|
| 001019 |
Immunotherapy of hepatocellular carcinoma with autologous lymphokine-activated killer cells and/or recombinant interleukin-2. |
Ishikawa T, Imawari M, Moriyama T, Ohnishi S, Matsuhashi N, Suzuki G, Takaku F. |
J Cancer Res Clin Oncol. |
114(3):283-90. |
1988 |
2838488 |
比較 |
肝 |
5 |
|
| 001020 |
The effects of localized therapy with postsurgical local recurrences of lung carcinoma and metastatic lung tumors--laser irradiation, IL-2+ LAK or ethanol injection |
Baba M, Yamaguchi Y, Fujisawa T, Kimura H. |
Gan To Kagaku Ryoho. |
15(4 Pt 2-2):1342-50. |
1988 |
3260090 |
単群 |
肺 |
6 |
|
| 001022 |
Adoptive immunotherapy of patients with metastatic renal cell cancer using lymphokine-activated killer cells, interleukin-2 and cyclophosphamide: long-term results. |
Tomita Y, Katagiri A, Saito K, Imai T, Saito T, Tanikawa T, Terunuma M, Nishiyama T, Takahashi K. |
Int J Urol. |
5(1):16-21. |
1998 |
9535595 |
単群 |
腎 |
9 |
|
| 001023 |
進行卵巣癌に対する活性化T Cell（CD3-AT)を用いた養子免疫療法の治療効果 |
竹田省 |
J. Jpn. Soc. Ther. |
30(7): 967-971 |
1995 |
|
単群 |
女性生殖器 |
4 |
|
| 001024 |
術後CBDCA,DTIC,VDS療法および養子免疫療法を施行した外陰および膣のⅢ期悪性黒色腫の1例 |
竹田省、池羽一紀、高木章美、木下勝之、栗原卓也、設楽幸伸、渡辺正寿、菅原勇、糸山進次、鈴木博宣、木村昌行、関根暉彬
|
Biotherapy |
11：567-70 |
1997 |
|
単群 |
悪性黒色腫 |
1 |
|
| 001025 |
Adjuvant Adoptive Immunotherapy Against Hepatocellular Carcinoma |
Takayama T, Sekine T, Kondo Y, Kakizoe T, Makuuchi M. |
Hepatology. |
28(5):1436-7. |
1998 |
9794935 |
単群 |
肝 |
1 |
|
| 001026 |
胞巣状軟部肉腫肺転移症例に対する養子免疫療法 |
加藤洋一,関根暉彬,藤井雅志 |
Biotherapy |
12(5):685-7 |
1998 |
|
単群 |
骨・軟部 |
1 |
|
| 001027 |
慢性C型肝炎および肝癌の活性化自己リンパ球投与療法 |
関根暉彬・高山忠利 |
化学療法の領域 |
15（3）：65-9 |
1999 |
|
比較 |
肝 |
142 |
|
| 001028 |
固層化CD3抗体活性化リンパ球を用いた悪性脳腫瘍の治療経験 |
渋井壮一郎、田中 実、野村和弘、関根暉彬 |
BCG・BRM療法研究会会誌 |
23：39-45 |
1999 |
|
単群 |
脳 |
5 |
|
| 001029 |
Six-year Disease-free Survival of a Patient with Metastatic Eyelid Squamous Cell Carcinoma and Colon Adenocarcinoma after Repeated Postoperative Adoptive Immunotherapy |
Kawamura A Jr, Sekine T, Sekiguchi M, Yanoma S, Kaneko A, Haneda T, Moriya Y, Hayasaka K, Kakizoe T. |
Jpn J Clin Oncol. |
30(6):267-71. |
2000 |
10939431 |
単群 |
その他 |
1 |
|
| 001030 |
当科における活性化自己リンパ球移入療法の治療成績 |
小川健治，出口義雄，勝部隆男，渡辺修，遠藤俊吾，梶原哲郎，黒岩保幸，山口智宏，馬場憲三，関根暉彬 |
Biotherapy |
15(3):217 |
2001 |
|
単群 |
脳、肺、大腸、乳、女性生殖器、膵、腎、膀胱、男性生殖器、肝、胆、皮膚、造血器、その他 |
29（2+3+4+2+2+1
+1+2+2+1+1+1+1+1） |
|
| 001031 |
活性化リンパ球 ○エビデンスに基づいたバイオセラピィの有用性○ |
高山忠利、関根暉彬 |
Biotherapy |
16（1）：61-4 |
2002 |
|
比較 |
肝 |
150 |
|
| 001032 |
Prospective randomized trial of high-dose interleukin-2 alone or in conjunction with lymphokine-activated killer cells for the treatment of patients with advanced cancer. |
Rosenberg SA, Lotze MT, Yang JC, Topalian SL, Chang AE, Schwartzentruber DJ, Aebersold P, Leitman S, Linehan WM, Seipp CA, et al. |
J Natl Cancer Inst. |
85(8):622-32. |
1993 |
8468720 |
比較 |
皮膚、腎、大腸、造血器、その他 |
174（49+97+18+7+3） |
|
| 001033 |
Prolonged continuous intravenous infusion interleukin-2 and lymphokine-activated killer-cell therapy for metastatic renal cell carcinoma. |
Thompson JA, Shulman KL, Benyunes MC, Lindgren CG, Collins C, Lange PH, Bush WH Jr, Benz LA, Fefer A. |
J Clin Oncol. |
10(6):960-8. |
1992 |
1588376 |
比較 |
腎 |
42 |
|
| 001034 |
Intraperitoneal lymphokine-activated killer-cell and interleukin-2 therapy for malignancies limited to the peritoneal cavity. |
Steis RG, Urba WJ, VanderMolen LA, Bookman MA, Smith JW 2nd, Clark JW, Miller RL, Crum ED, Beckner SK, McKnight JE, et al. |
J Clin Oncol. |
8(10):1618-29. |
1990 |
2213099 |
単群 |
女性生殖器、大腸 |
22（10+12） |
|
| 001036 |
A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone. |
Rosenberg SA, Lotze MT, Muul LM, Chang AE, Avis FP, Leitman S, Linehan WM, Robertson CN, Lee RE, Rubin JT, et al. |
N Engl J Med. |
316(15):889-97. |
1987 |
3493432 |
比較 |
腎、皮膚、大腸、造血器、骨・軟部、肺、その他 |
152（57+42+32
+2+6+6+7） |
|
| 001037 |
A new approach to the therapy of cancer based on the systemic administration of autologous lymphokine-activated killer cells and recombinant interleukin-2. |
Rosenberg SA, Lotze MT, Muul LM, Leitman S, Chang AE, Vetto JT, Seipp CA, Simpson C. |
Surgery. |
100(2):262-72. |
1986 |
3526604 |
単群 |
大腸、皮膚、腎、骨・軟部、肺、食道、造血器、胃 |
41（14+10+5+5
+4+1+1+1） |
|
| 001038 |
Adoptive Immunotherapy to Lower Postsurgical Recurrence Rates of Hepatocellular Carcinoma:A Randomised trial. |
Takayama T, Sekine T, Makuuchi M, Yamasaki S, Kosuge T, Yamamoto J, Shimada K, Sakamoto M, Hirohashi S, Ohashi Y, Kakizoe T. |
Lancet. |
356(9232):802-7. |
2000 |
11022927 |
比較 |
肝 |
150 |
|
| 001039 |
A phase Ⅲ randomized sutdy of intterleukin-2 lymphokine-activated killer cell immunotherapy combined with chemotherapy or radiotherapy after curative or noncurative resection of primary lung carcinoma. |
Kimura H, Yamaguchi Y. |
Cancer. |
80(1):42-9. |
1997 |
9210707 |
比較 |
肺 |
174 |
|
| 001040 |
Prognostic Significance of Adoptive Immunotherapy with tumor associated Lymphocytes in Patients with Advanced Gastric Cancer:A Randomized Trial. |
Kono K, Takahashi A, Ichihara F, Amemiya H, Iizuka H, Fujii H, Sekikawa T, Matsumoto Y. |
Clin Cancer Res. |
8(6):1767-71. |
2002 |
12060615 |
比較 |
胃 |
44 |
|
| 001041 |
Life-prolonging effect of immunocell BAK (BRM-activated killer) therapy for advanced solid cancer patients: prognostic significance of serum immunosuppressive acidic protein levels.
|
Ebina T, Ogama N, Shimanuki H, Kubota T, Isono N. |
Cancer Immunol Immunother. |
52(9):555-60. |
2003 |
14627127 |
単群 |
肺、膵、女性生殖器、大腸、胃、頭頸部、乳、胆、腎、食道、男性生殖器、その他 |
65（15+2+8+9+6+2
+10+1+4+2+2+4） |
|
| 001042 |
Induction of autologous tumor-specific cytotoxic T cells in patients with liver cancer. Characterizations and clinical utilization. |
Aruga A, Yamauchi K, Takasaki K, Furukawa T, Hanyu F. |
Int J Cancer. |
49(1):19-24. |
1991 |
1678733 |
単群 |
肝 |
15 |
|
| 001043 |
Distribution and therapeutic effect of intraarterially transferred tumor infiltrating lymphocytes in hepatic malignancies. preliminary report |
Takayama T, Makuuchi M, Sekine T, Terui S, Shiraiwa H, Kosuge T, Yamazaki S, Hasegawa H, Suzuki K, Yamagata M, et al. |
Cancer. |
68(11):2391-6. |
1991 |
1657353 |
単群 |
肝 |
3 |
|
| 001044 |
Locoregional cellular immunotherspy for patients with asvanced esophageal cancer |
Toh U, Yamana H, Sueyoshi S, Tanaka T, Niiya F, Katagiri K, Fujita H, Shirozou K, Itoh K. |
Clin Cancer Res. |
6(12):4663-73. |
2000 |
1156218 |
単群 |
食道 |
11 |
|
| 001045 |
Chemo-immunotherapy and chemo-adoptive-immunitherapy of cancer |
Gomez GG, Hutchison RB, Kruse CA. |
Cancer Treat Rev. |
27(6):375-402. |
2001 |
11908930 |
比較 |
皮膚、肝 |
60(36+24) |
○ |
| 001047 |
Adoptive immunotherapy for unresectable or recurrent pancreatic cancer, using lymphokine-activated killer cells or cytotoxic T cells |
Masaaki Oka, Michinari Suzuki, Shoichi Hazama and Takashi Suzuki |
Hepato-Biliary-Pancreatic Surgery |
Volume 1, Number 2:163 - 167 |
1994 |
|
比較 |
膵 |
3 |
|
| 001048 |
Adoptive immunotherapy for pancreatic cancer ,using MUC1 specific CTL. |
Masaki Y, Oka M. |
Gan To Kagaku Ryoho. |
23(12):1679-80. |
1996 |
8886044 |
単群 |
膵 |
3 |
|
| 001049 |
Effect of intraportal adoptiveimmuntherspt on liver metastases after resection of pancreatic cancer. |
Kobari M, Egawa S, Shibuya K, Sunamura M, Saitoh K, Matsuno S. |
Br J Surg. |
87(1):43-8. |
2000 |
10606909 |
比較 |
膵 |
29 |
|
| 001050 |
膵臓に対する養子免疫療法 |
鈴木道成 、 岡正朗 、 他 |
胆 と 膵 |
16:509-16 |
1995 |
|
比較 |
膵 |
8 |
|
| 002001 |
clinical Benefit of Non-toxic Therapy in Patients with Advanced Cancer |
Goto S, Shirotani N, Hatakeyama M, Tagami C, Arakawa H, Kuwata E, Noguchi K, Egawa K. |
Anticancer Res. |
22(4):2461-4. |
2002 |
12174944 |
比較 |
肺、乳、胃、女性生殖器、頭頸部、肝、男性生殖器、大腸、食道、皮膚、その他 |
75（20+9+8+6+5+4
+4+3+3+2+11） |
|
| 002002 |
Tumor-derived interleukin-2-dependent lymphocytes in adoptive immunotherapy of lung cancer |
Kradin RL, Boyle LA, Preffer FI, Callahan RJ, Barlai-Kovach M, Strauss HW, Dubinett S, Kurnick JT. |
Cancer Immunol Immunother. |
24(1):76-85. |
1987 |
3493073 |
単群 |
肺 |
7 |
|
| 002003 |
effect of autolymphocyte therapy on survival and quality of life in patients with metastatic renal-cell carcinoma |
Osband ME, Lavin PT, Babayan RK, Graham S, Lamm DL, Parker B, Sawczuk I, Ross S, Krane RJ |
Lancet. |
335(8696):994-8. |
1990 |
1970108 |
比較 |
腎 |
90 |
|
| 002004 |
Adoptive Chemoimmunotherapy for the Treatment of Relapsed and Refractory Solid Tumors Using Ex Vivo Activated Memory T cells (autolymphocyte Therapy) and Cyclophosphamide |
Gold JE, Malamud SC, LaRosa F, Seder R, Osband ME. |
J Immunother. |
13(3):213-21. |
1993 |
8471596 |
単群 |
肺、頭頸部、皮膚、骨・軟部、膀胱 |
21（8+2+6+4+1） |
|
| 002005 |
Adoptive Transfer of EX Vivo Activated Memory T-cells With or Withiout Cyclophosphamide for Advanced Metastatic Melanoma:Results in 36 Patients. |
Gold JE, Ross SD, Krellenstein DJ, LaRosa F, Malamud SC, Osband ME. |
Eur J Cancer. |
31A(5):698-708. |
1995 |
7640041 |
比較 |
悪性黒色腫 |
36 |
|
| 002006 |
Phase Ⅲ Randomized Trial of Interleukin-2 with or without lymphokine-Activated Killer Cells in the Treatment of Patients with Advanced Renal Cell Carcinoma |
Law TM, Motzer RJ, Mazumdar M, Sell KW, Walther PJ, O'Connell M, Khan A, Vlamis V, Vogelzang NJ, Bajorin DF. |
Cancer. |
76(5):824-32. |
1995 |
8625186 |
比較 |
腎 |
71 |
|
| 002009 |
REGRESSION OF METASTATIC RENAL-CELL CARCINOMA AFTER NONMYELOABLATIVE ALLOGENEIC PERIPHERAL-BLOOD STEM-CELL TRANSPLANTATION |
Childs R, Chernoff A, Contentin N, Bahceci E, Schrump D, Leitman S, Read EJ, Tisdale J, Dunbar C, Linehan WM, Young NS, Barrett AJ. |
N Engl J Med. |
343(11):750-8. |
2000 |
10984562 |
単群 |
腎 |
19 |
|
| 002030 |
細胞療法 |
角田卓也,高山卓也,田原秀晃 |
臨外 |
57（7）：971-5 |
2002 |
|
比較 |
肝 |
170 |
○ |
| 002041 |
Adoptive immu n otherapy to lower postsurgical recurrence rates of hepatocellular carcinoma:a randomised trial |
Takayama T, Sekine T, Makuuchi M, Yamasaki S, Kosuge T, Yamamoto J, Shimada K, Sakamoto M, Hirohashi S, Ohashi Y, Kakizoe T. |
Lancet. |
356(9232):802-7. |
2000 |
11022927 |
比較 |
肝 |
150 |
|
| 002044 |
Efficacy of Immuno-cell Therapy in Patients with Advanced Pancreatic Cancer |
Kaneko T, Goto S, Kato A, Akeyama A, Tomonaga M, Fujimoto K, Miyamoto Y, Eriguchi M, Egawa K. |
Anticancer Res. |
25(6A):3709-14. |
2005 |
16302730 |
単群 |
膵 |
46 |
|
| 002047 |
悪性神経膠腫に対するCTL precursor-oriented ペプチドワクチン療法 |
矢島直樹 |
日本臨牀社増刊号脳腫瘍の診断と治療 |
878：Ⅳ.8.7）.582 |
2005 |
|
単群 |
脳 |
9 |
|
