がん治療・がんに対する免疫細胞療法専門クリニック
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  [樹状細胞療法のClinical trial]に関する参考文献    

   参考文献はこちら(PDF)です。文献の詳細は下記の一覧に載っております。

 
File No Title Author Journal Vol&Page Year Pub Med ID Study 疾患 症例数 Review
002010 Phase I clinical trial: T-cell therapy for prostate cancer using autologous dendritic cells pulsed with HLA-A0201-specific peptides from prostate-specific membrane antigen. Murphy G, Tjoa B, Ragde H, Kenny G, Boynton A. Prostate. 29(6):371-80. 1996 8977634 比較 男性生殖器 20-25   
002011 A phase Tstudy of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer Iwashita Y, Tahara K, Goto S, Sasaki A, Kai S, Seike M, Chen CL, Kawano K, Kitano S. Cancer Immunol Immunother. 52(3):155-61. Epub 2003 Feb 6. 2003 12649744 単群 10   
002012 Phease T/U study of treatment with dendritic cell vaccines in patients with disseminated melanoma Hersey P, Menzies SW, Halliday GM, Nguyen T, Farrelly ML, DeSilva C, Lett M. Cancer Immunol Immunother. 53(2):125-34. Epub 2003 Nov 5. 2004 14600790 比較 悪性黒色腫 33   
002013 Vaccination of melanoma patients with peptide -or tumor lysate-pulsed dendritic cells Nestle FO, Alijagic S, Gilliet M, Sun Y, Grabbe S, Dummer R, Burg G, Schadendorf D. Nat Med. 4(3):328-32. 1998 9500607 単群 悪性黒色腫 16   
002014 Dendritic cell immunotherapy in a neuroendocrine pancreas carcinoma Schott M, Feldkamp J, Lettmann M, Simon D, Scherbaum WA, Seissler J. Clin Endocrinol (Oxf). 55(2):271-7. 2001 11531937 単群 1   
002015 Vanccination with autologous tumour santigen-pulsed dendritic cells in advanced gynaecological malignancies: clinical and immunological evaluation of a phase Ttrial Hernando JJ, Park TW, Kubler K, Offergeld R, Schlebusch H, Bauknecht T. Cancer Immunol Immunother. 51(1):45-52. Epub 2002 Jan 10. 2002 11845259 単群 女性生殖器 8   
002016 Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells Hsu FJ, Benike C, Fagnoni F, Liles TM, Czerwinski D, Taidi B, Engleman EG, Levy R. Nat Med. 2(1):52-8. 1996 8564842 単群 造血器 4   
002017 Infusion of Dendritic Cells Pulsed With HLA-A2-Specific Prostate-Specific membrane Antigen Peptides :A Phase UProstate Cancer Vaccine Trial Involving Patients With Hormone-Refractory Metastatic Disease Murphy GP, Tjoa BA, Simmons SJ, Jarisch J, Bowes VA, Ragde H, Rogers M, Elgamal A, Kenny GM, Cobb OE, Ireton RC, Troychak MJ, Salgaller ML, Boynton AL. Prostate. 38(1):73-8. 1999 9973112 単群 男性生殖器 33   
002018 A PhaseTstudy of Active Immunotherapy with Carcinoembryonic Antigen Peptide (CAP-1) -pulsed,Autologous Human Cultured Dendritic Cells in Patients with Matastatic Malignancies Expressing Carcinoembryonic Antigen Morse MA, Deng Y, Coleman D, Hull S, Kitrell-Fisher E, Nair S, Schlom J, Ryback ME, Lyerly HK. Clin Cancer Res. 5(6):1331-8. 1999 10389916 比較 大腸、乳、女性生殖器、膵、その他 105(21+21+21+21+21)   
002019 Priming Tissue-specific Cellular Immunity in a PhaseTtrial of Autologous Dendritic Cells for Prostate Cancer Burch PA, Breen JK, Buckner JC, Gastineau DA, Kaur JA, Laus RL, Padley DJ, Peshwa MV, Pitot HC, Richardson RL, Smits BJ, Sopapan P, Strang G, Valone FH, Vuk-Pavlovic S. Clin Cancer Res. 6(6):2175-82. 2000 10893066 比較 男性生殖器 13   
002020 PheaseTStudy in Patients With Metastatic Melanoma of Immunization With Dendritic Cells Presenting Epitopes Derived From the Melanoma-Associated Antigens MART-1 and gp100 Panelli MC, Wunderlich J, Jeffries J, Wang E, Mixon A, Rosenberg SA, Marincola FM. J Immunother. 23(4):487-98. 2000 10916759 比較 悪性黒色腫 10   
002021 PHASETSTUDY IN MELANOMA PATIENTS OF A VACCINE WITH PEPTIDE=PULSED DENDRITIC CELLS GENERATED IN VITRO FROM CD34 HEMATOPOIETIC PROGENITOR CELLS Mackensen A, Herbst B, Chen JL, Kohler G, Noppen C, Herr W, Spagnoli GC, Cerundolo V, Lindemann A. Int J Cancer. 86(3):385-92. 2000 10760827 単群 悪性黒色腫 14   
002022 Intratumoral Imjection of Dendritic Cells Derived In Vitro in Patients with Metastatic Cancer Triozzi PL, Khurram R, Aldrich WA, Walker MJ, Kim JA, Jaynes S. Cancer. 89(12):2646-54. 2000 11135227 単群 悪性黒色腫、乳 10(7+3)   
002023 PhaseTTrial Of Intravenous Peptide-Pulsed Dendritic Cells in Patients With Metastatic Melanoma Lau R, Wang F, Jeffery G, Marty V, Kuniyoshi J, Bade E, Ryback ME, Weber J.   J Immunother. 24(1):66-78. 2001 11211150 単群 悪性黒色腫 16   
002024 Dendritic Cell Vaccination with MAGE Peptide Is A Novel Therapeutic Approach for Gastrointestinal Carcinomas Sadanaga N, Nagashima H, Mashino K, Tahara K, Yamaguchi H, Ohta M, Fujie T, Tanaka F, Inoue H, Takesako K, Akiyoshi T, Mori M. Clin Cancer Res. 7(8):2277-84. 2001 11489802 単群 胃、食道、大腸 12(6+3+3)  
002025 Immune and Clinical Responses in Patients with Metastatic Melanoma to CD34 Progenitor-derived Dendritic Cell Vaccine Banchereau J, Palucka AK, Dhodapkar M, Burkeholder S, Taquet N, Rolland A, Taquet S, Coquery S, Wittkowski KM, Bhardwaj N, Pineiro L, Steinman R, Fay J. Cancer Res. 61(17):6451-8. 2001 11522640 単群 悪性黒色腫 18  
002026 A PhaseTTrial of Tumor Lysate-pulsed Dendritic Cells in the Treatment of Advanced Cancer Chang AE, Redman BG, Whitfield JR, Nickoloff BJ, Braun TM, Lee PP, Geiger JD, Mule JJ. Clin Cancer Res. 8(4):1021-32. 2002 11948109 単群 悪性黒色腫、大腸、その他 14(11+2+1)  
002027 第2世代樹状細胞(DC)局所療法の臨床研究 谷川啓司,清水公一,藤沢俊美.有賀淳,Mule James,高崎健 Biotherapy 15 (suppl.U):54 2001   単群 その他 16  
002028 Dendritic Cells Pulsed with HER-2/neu-derived Paptides Can Induce Specific T-Cell Responses in Patients with Gastric Cancer Kono K, Takahashi A, Sugai H, Fujii H, Choudhury AR, Kiessling R, Matsumoto Y. Clin Cancer Res. 8(11):3394-400. 2002 12429626 単群 9  
002029 Therapeutic vaccination against metastatic renal cell carcinoma by autologous dendritic cells: preclinical results and outcome of a first clinical phaseT/U trial Marten A, Flieger D, Renoth S, Weineck S, Albers P, Compes M, Schottker B, Ziske C, Engelhart S, Hanfland P, Krizek L, Faber C, von Ruecker A, Muller S, Sauerbruch T, Schmidt-Wolf IG. Cancer Immunol Immunother. 51(11-12):637-44. Epub 2002 Oct 3. 2002 12439609 単群 15  
002030 細胞療法 角田卓也,高山卓也,田原秀晃 臨外 57(7):971-5 2002   比較 皮膚、腎、その他 120(64+50+6)
002031 固形癌に対する細胞免疫療法−樹状細胞を用いた癌ワクチン療法− 上田祐二、山岸久一 京都医大誌 111(6):487-99 2002   単群 大腸、胃、肺 16(10+2+4)  
002032 固形癌に対する細胞免疫療法の現況と展望 山岸久一 松仁会医学誌 41(2):99-109 2002   単群 大腸、胃、肺 16(10+2+4)
002033 Results of a PhaseTclinical study using autologous tumour lysate-pulsed monocyte-derived mature dendritic cell vaccinations for stage W malignant melanoma patients combined with low dose interleukin-2 Nagayama H, Sato K, Morishita M, Uchimaru K, Oyaizu N, Inazawa T, Yamasaki T, Enomoto M, Nakaoka T, Nakamura T, Maekawa T, Yamamoto A, Shimada S, Saida T, Kawakami Y, Asano S, Tani K, Takahashi TA, Yamashita N. Melanoma Res. 13(5):521-30. 2003 14512794 単群 悪性黒色腫 10  
002034 Dendritic cell vaccination for patients with chronic myelogenous leukemia Takahashi T, Tanaka Y, Nieda M, Azuma T, Chiba S, Juji T, Shibata Y, Hirai H. Leuk Res. 27(9):795-802. 2003 12804637 単群 造血器 3  
002035 Vaccination of recurrent glioma patient with tumour lysate-pulsed dendritic cells elicits immune responses: results of a clinical phase T/Utrial Yamanaka R, Abe T, Yajima N, Tsuchiya N, Homma J, Kobayashi T, Narita M, Takahashi M, Tanaka R. Br J Cancer. 89(7):1172-9. 2003 14520441 単群 その他 10  
002036 A pilot Trial of Tumor Lysate-Loaded Dendritic cells for the Treatment of Metastatic Renal Cell Carcinoma Gitlitz BJ, Belldegrun AS, Zisman A, Chao DH, Pantuck AJ, Hinkel A, Mulders P, Moldawer N, Tso CL, Figlin RA. J Immunother. 26(5):412-9. 2003 12973030 単群 14  
002037 Dendritic cell-based tumor vaccine for cervical cancer U: results of a clinical pilot study in 15 individual patients Ferrara A, Nonn M, Sehr P, Schreckenberger C, Pawlita M, Durst M, Schneider A, Kaufmann AM. J Cancer Res Clin Oncol. 129(9):521-30. Epub 2003 Jul 30. 2003 12898233 単群 女性生殖器 15  
002038 Dendritic Cells Injected Via Different Routes Induce Immunity in Cancer Patients Fong L, Brockstedt D, Benike C, Wu L, Engleman EG. J Immunol. 166(6):4254-9. 2001 11238679 単群 男性生殖器 21  
002039 Vaccination of Patients With Metastatic Renal Cell Carcinoma With Autologous Dendritic Cells Pulsed With Autologous Tumor Antigens in Combination With Interleukin-2: A phase TStudy Oosterwijk-Wakka JC, Tiemessen DM, Bleumer I, de Vries IJ, Jongmans W, Adema GJ, Debruyne FM, de Mulder PH, Oosterwijk E, Mulders PF. J Immunother. 25(6):500-8. 2002 12439347 単群 12  
002045 Clinical response in Japanese metastatic melanoma patients treated with peptide cocktail-pulsed dendritic cells. Akiyama Y, Tanosaki R, Inoue N, Shimada M, Hotate Y, Yamamoto A, Yamazaki N, Kawashima I, Nukaya I, Takesako K, Maruyama K, Takaue Y, Yamaguchi K. J Transl Med. 3(1):4. 2005 15676080 単群 悪性黒色腫 9  
002046 Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy. de Vries IJ, Lesterhuis WJ, Barentsz JO, Verdijk P, van Krieken JH, Boerman OC, Oyen WJ, Bonenkamp JJ, Boezeman JB, Adema GJ, Bulte JW, Scheenen TW, Punt CJ, Heerschap A, Figdor CG. Nat Biotechnol. 23(11):1407-13. Epub 2005 Oct 30. 2005 16258544 単群 悪性黒色腫 11  
002048 A phase I study of alpha-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer. Ishikawa A, Motohashi S, Ishikawa E, Fuchida H, Higashino K, Otsuji M, Iizasa T, Nakayama T, Taniguchi M, Fujisawa T. Clin Cancer Res. 11(5):1910-7 2005 1575601 単群 11